The FDA has a fast-track system that gets animal drugs approved in 2 years instead of 10—but won't use it for humans, despite similar biology. Meanwhile, life-saving human vaccines stay stuck.
"We could treat tuberculosis deaths with the urgency they deserve by considering giving people at high risk of tuberculosis the option to try it after safety testing." - in the case of that vaccine, multiple Phase I safety trials have already been done! (https://elicit.com/notebook/addc826b-c504-4004-9abe-bb2f2fb59a4d)
"We could treat tuberculosis deaths with the urgency they deserve by considering giving people at high risk of tuberculosis the option to try it after safety testing." - in the case of that vaccine, multiple Phase I safety trials have already been done! (https://elicit.com/notebook/addc826b-c504-4004-9abe-bb2f2fb59a4d)
Thanks for reminding me about that post by Jacob Trefethen, "10 technologies that won't exist in 5 years" -- what a "banger"! (https://blog.jacobtrefethen.com/10-technologies-that-wont-exist-in-5-yrs/)
Yes creativity and speed combined with safety and efficacy are paramount. Thank you for this article. There is a research company in UT working with AI models to speed up path to clinical trials, which I mention in a recent article - https://jaredmoss.substack.com/p/shocking-how-one-family-turned-tragedy?r=5v0srs